An Efficacy of Anti-hyperglycemic Agents (Nigella sativa) in Blood, Body Weight and Glucose levels of Diabetes Mellitus Rats: A Comprehensive Review
An Efficacy of Anti-hyperglycemic Agents (Nigella sativa) in Blood, Body Weight and Glucose levels of Diabetes Mellitus Rats: A Comprehensive Review
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Date
2023-01
Authors
Ofori,S.A
Yeboah,E.O
Amissah-Reynolds,P.K
Owusu,P
Amankwah Philip
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Publisher
International Journal of Health Sciences and Research
Abstract
There is a large global trend toward the use of medicinal herbs for the treatment of diabetes, and many
people employ complementary and alternative medicine. The objective of the study was to provide
comprehensive information on the effects of Nigella sativa on lipid profile, glucose level, and body
weight in diabetic-induced rats. This is a comprehensive review carried out through PubMed, Science
Direct, Google scholar and Springer and other Scientific Electronic Library Online databases, using
the keywords; “N. sativa”, “black seed”, “diabetes”, “glucose”, “lipid”, “Weight”, and “insulin”
associated with the Boolean operator “AND”. At first, 241 articles from 2000 to 2022 were
discovered. Following the application of the specified inclusion and exclusion criteria, 21 papers were
still available, and 15 underwent complete reading, after which all were included in the study.
According to their findings, N. sativa has a variety of possible mechanisms for controlling
hyperglycemia and abnormal lipid profiles, including its antioxidant properties and influences on
insulin secretion, glucose absorption and body weight. However, further clinical studies are required
to determine the N. sativa therapeutic benefits, as well as the kind and dose that work best for
managing diabetes and its consequences.
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Citation
Ofori, S. A., Yeboah, E. O., Amissah-Reynolds, P. K., Owusu, P., & Philip, A. An Efficacy of Anti-hyperglycemic Agents (Nigella sativa) in Blood, Body Weight and Glucose levels of Diabetes Mellitus Rats: A Comprehensive Review.